With the availability of highly effective ARV drugs to combat HIV/AIDS, the morbidity and mortality from these conditions have reduced significantly. Although it’s still a global epidemic with no cure at the moment, the HIV infection can be treated.
ARV meds drastically reduce viral load in the patients’ body, helping them live a longer and healthier life.
HIV treatment involves a comprehensive assessment of the patient’s health and administering a safe drug with periodic assessment of viral load while under medication.
Naivex is produced by the Indian pharmaceutical manufacturer, Hetero. Here is the full detail on how to use these anti-HIV tablets.
Naivex 50 mg Uses
Dolutegravir is a highly potent drug that’s used with another ARV meds to treat HIV. Naivex 50 mg is one of generic versions of Tivicay containing dolutegravir as an active substance.
It functions by decreasing the chance of getting HIV complications by improving the patient’s quality of life and boosting their immune system.
Naivex is prescribed to:
- treatment-naïve patients – those who have never taken HIV drugs;
- treatment-experienced – those who have previously administered anti-HIV therapy;
- adult patients who have been medicated with other INSTI drugs.
There are other off-label uses of dolutegravir (including nPEP) in combination with other antiretrovirals.
How Does This Medicine Work?
The primary function of the Naivex active substance (dolutegravir) is to block the viral integrase enzyme, thus preventing the virus from multiplying.
HIV uses the integrase enzyme to insert its viral DNA into the DNA of the host T-cell. By blocking the integrase action in the CD4 cell nucleus, its replication process is terminated. However, it cannot fully cure the already infected T-cells.
Best Way to Take Naivex 50 mg
Naivex containing dolutegravir comes in various dose strength and should be taken according to the doctor’s prescription. Prior health assessment is mandatory before starting the treatment.
Take Naivex 50 mg with or without foods. It’s a must to take this drug together with other anti-HIV medicines. The pills should not be broken, chewed, or crushed when taking.
For adults, either new or INSTI-experienced, take the 50 mg tab twice a day with another strong UGT1A or CYP3A inducers such as Efavirenz, Ritonavir, or Rifampin.
For pediatric individuals aged 12 years and older and weighing at least 40 kg, either new or already treated, but not with INSTI, the recommended dose of Naivex 50 mg is 1 tab a day. If combined with the above-mentioned drugs, the suggested dose is 1 pill taken twice daily.
Common Side Effects
To prevent potential side effects, it’s necessary to let the doctor assess your health for possible illnesses and drug interactions. Adherence to prescription is paramount.
While using this med, common side effects such as these can occur:
- loss of appetite;
- increased bilirubin, blood glucose level, creatine kinase, and lipase;
- acute liver failure/toxicity;
- abnormal dreams;
Severe adverse reactions may include:
- hypersensitivity reactions;
- elevation of hepatic enzymes;
- immune reconstitution inflammatory syndrome.
Precautions are necessary when administering Naivex. Let your doctor know about the following:
- allergy to dolutegravir or any other INSTI med;
- using hormone-based birth control;
- liver problems, including hep B and hep C virus infection;
- breastfeeding or pregnancy.
In case you experience any of the above side effects or any other strange condition, inform your medical specialist for assistance.
Interaction with Food, Alcohol and Other Pills
Some foods such as Seville orange, grapefruit or juice made of it, garlic as well as calcium supplements may cause minor food-drug interactions to occur. Multivitamins with minerals cause major interactions. This type of diet can be adhered to only after getting directions from a medical specialist.
Drug interactions include:
- Dofetilide, Metformin, or other meds excreted through OCT2 or MATE1;
- some herbal products;
- Etravirine and other NNRTIs;
- protease inhibitors;
- substrates of UGT1A9, UGT1A3, BCRP & P-gp transporters.
Dolutegravir interacts with 143 meds, of which 55 cause major drug interactions. Disease interactions include liver impairment and hepatitis.
Always give a complete list of all the drugs you are using to your medical specialist to analyze for potential interactions, be it OTC drugs, herbal remedies including vitamins, prescription meds, or recreational drugs.
Testimonials and Reviews About Drug Effectiveness
Naivex is a cost-effective anti-HIV med that helps millions of people who would have spent hundreds of dollars medicating with Tivicay.
Being a generic, it’s approved by the U.S. FDA and acknowledged by healthcare providers as being among the top anti-HIV drugs due to its high efficacy and tolerability. Most people who use this med report the improved CD4+ cell count and substantial viral load suppression.
In combination with other anti-HIV meds, Naivex has proved itself to be the best second-generation INSTI. Side effects can exist but are well tolerated. From testimonials, most patients report fewer adverse reactions that usually fade away with continual use of the drug.
User reviews help determine the efficacy, ease of use and tolerability of Naivex 50 mg. It’s an individual opinion. You should discuss and take medication according to the doctor’s prescription and not solely based on the reviews.
At PrEPGeneric online drugstore, we urge you to leave an honest review of this drug usage and efficacy.
Where to Buy Cheap Tablets of Naivex 50 mg from India?
There are various ways to order anti-HIV medications. It can be from a local pharmacy or an online drugstore, and pricing in these places may vary. It’s best to find a reliable supplier that sells quality Naivex 50 mg pills at an affordable cost.
At our online pharmacy, we sell this drug over the counter at more than 95% cheaper compared to the price of a brand-name tabs.
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If your doctor prescribed you dolutegravir, the PrEPGeneric pharmacy has quality approved Naivex. Get it at a substantially lower price and safely medicate HIV in the body. We are the leading provider of quality anti-HIV and PrEP meds. Take action now! Order generic Naivex 50 mg tablets and save hundreds of dollars.