HIV treatment is no longer expensive. Tafero-EM is a cost-effective generic drug approved to keep the virus from replicating. It is a highly potent anti-HIV med known to have a safety profile.
Before proceeding to order 360 tabs of Tafero-EM, it’s necessary to know how the med is administered. Get to know its benefits, negative effects and interactions, as well as where to order quality drugs from a trusted online pharmacy. Some drugs bought online can be fake. Here is the full detail.
Produced by Hetero, one of the top manufacturers of antiretroviral drugs, and approved by Drug Controller General of India (DCGI), Tafero-EM became the first generic version of Descovy. It’s a fixed dose of emtricitabine (EM) and tenofovir alafenamide (TAF).
TAF is a prodrug of tenofovir (TFV), identified as an alternative to tenofovir disoproxil fumarate (TDF), with improved safety benefits – comparatively free of the adverse effects to the bone and renal problems commonly associated with TDF.
Through research, studies and recommendations by various medicine guidelines, Tafero-EM is becoming a preferred generic dual-NRTI backbone used along with a third medicine that has a different mechanism of action to TAF/EM.
HIV has no cure at the moment, but the safety, effectiveness and cheap price of Tafero-EM makes it one of the most preferred choices for thousands of people undergoing HIV treatment. This drug can be used by patients who have previously received treatment with other anti-HIV meds or by those looking for a treatment for the first time.
Here is the full detail on Tafero-EM uses, its side effects, and drug interactions as well as how you can easily buy 360 tablets at an extremely low cost.
How Does Tafero-EM Work?
HIV can replicate fast in the body. Without an effective treatment to combat this process, a patient’s immune system can drastically weaken and possess a risk of other opportunistic, life-threatening infections or diseases.
Tafero-EM tablets are the ideal drug needed to prevent the virus from spreading. This med is highly effective against RNA viruses (or retroviruses) such as HIV. It works by targeting and inhibiting the activity of reverse transcriptase (RT), which is a key component needed for the virus to be able to duplicate or replicate.
TAF is a NtRTI and a more efficient component than TDF in concentrating tenofovir in the virus target cells (up to 90% decrease in plasma tenofovir concentrations). Emtricitabine is an NRTI that works together with TAF to block or prevent the action of RT, which is required to transcribe the viral RNA into DNA. Tafero-EM attaches itself to the chain of newly synthesized viral DNA and effectively terminates its chain or prevents it from growing.
This mode of action decreases the viral load and slows down the multiplication of HIV in the patient’s body. It does not completely kill the virus already incorporated in the T-cells. Continual use of Tafero-EM lowers the virus viral load and increases the CD4+ count. Increased levels of CD4 cells make the immune system stronger, resulting in better health even while leaving with the virus.
How Should You Take Tafero-EM Tabs?
As a fixed-dose drug used in combination with another antiretroviral med, only 1 tablet is taken per day with a glass of water. It should also be administered with food, not on an empty stomach. Make sure to be assessed by a doctor before taking anti-HIV meds.
Prior to using this med, you should be tested for the presence of hepatitis B and investigate the renal values, including creatinine clearance, glucose, and protein in the urine.
This medication is prescribed for patients weighing above 35 kg whose creatinine clearance is 30 mL/min or greater. Individuals having a creatinine clearance less than 30 mL/min should not take this fixed-dose drug.
For high effectiveness in managing the viral load and boosting the immune system, take this med exactly as prescribed by your medical specialist. While under medication, you are obliged to the routine CD4+ count and viral load monitoring.
Do not stop this TAF/EM treatment abruptly as this may raise the risk of HIV resistance to medication. If you forget to take your daily tab at the right time, take it as soon as you remember (within 12 hours). If it’s approaching time to take your next dose, skip the missed dose and wait for the next tab.
Side Effects of Medication
Although TAF is a prodrug of TDF with a safety profile, side effects cannot be avoided. TAF in Tafero-EM works better in patients that had adverse reactions to the medications before, due to the bone and renal problems.
Common reported side effects include:
- sleeping difficulty;
- gastrointestinal discomfort;
- muscle stiffness;
- chest pain;
- skin discoloration;
- pain during urination;
A serious side effect of this medication is lactic acidosis due to liver damage. This condition elevates blood lactic acid levels, causing liver problems, pancreatitis, or renal failure. Other negative reactions may include kidney conditions, changes in the immune system, bone problems, increased cholesterol.
Your health is paramount. Keep track of these side effects and report to your medical specialist of any serious reactions, including the most known conditions that continue for long.
Tafero-EM is known to interact with more than 170 drugs (with 122 major drug-drug interactions) and 7 disease interactions. Drug-drug interactions cause a reduction in the TAF/EM drug effectiveness, hence affecting the patient therapeutic responses. It can also raise the risk of adverse conditions, which may be life-threatening.
Your doctor can give you a list of recommendations to safely used Tafero-EM without causing any interaction, which might cause harm to your health.
Common interactions include the following:
These interactions can either increase or decrease the functioning of Tafero-EM. Other interactions include antiepileptics like Phenytoin and Carbamazepine as well as retroviral meds such as Atazanavir, Ritonavir, and Didanosine. Also, herbal supplements such as St. John’s Wort should not be used while under TAF/EM treatment.
Disease interactions include:
- hepatitis B – due to discontinued administration of Tafero-EM;
- renal dysfunction;
- hepatotoxicity – due to the use of NRTIs or other antiretroviral agents;
- bone toxicity – possible decrease in BMD;
- hemodialysis – due to emtricitabine;
- liver disease – particularly for those experiencing impaired hepatic function.
If you have any of the above health conditions, let your doctor know. It’s necessary to keep monitoring, and if possible, drug adjustment can be recommended.
Reviews and Ratings
In fact, this drug works fine without any major risks. From our reviews, 90% of those who administered Tafero-EM pills report a remarkable decrease in their viral load and improvement in the CD4+ cell count. Some report an undetectable viral load in 3 months with continual use of this med.
If you need a med that does what’s intended to achieve, then this drug is highly recommended. It’s a great medicine with remarkable efficacy and improved tolerability, especially if you have renal and bone problems.
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